Michael A. Pritchett, DO, MPH

Pulmonology Specialist
Sleep Medicine Specialist

Phone: 910.295.9359
Fax: 910.234.3401

Biography

Education

  • Nova Southeastern University, Ft. Lauderdale, FL
    -Doctor of Osteopathy
  • St. Elizabeth’s Medical Center, Tufts University School of Medicine, Boston, MA
    -Pulmonary Disease and Critical Care Medicine Fellowship
  • Mount Sinai Medical Center, Miami Beach, FL
    -Internal Medicine Residency
  • Nova Southeastern University, Ft. Lauderdale, FL
    -Master in Public Health
  • University of Florida, Gainesville, FL
    -Bachelor of Science in Microbiology and Cell Science

Overview

Dr. Michael Pritchett is an advanced bronchoscopist who is board certified in pulmonary disease and critical care medicine. He received his undergraduate degree from the University of Florida. He then attended medical school at Nova Southeastern University where he simultaneously received his medical degree and a master's degree in public health. He completed his residency in Internal Medicine at Mt. Sinai Medical Center in Miami Beach, FL, and then his fellowship in Pulmonary & Critical Care Medicine at St. Elizabeth's Medical Center, Tufts University School of Medicine in Boston, MA.

Since completing fellowship, he has been in private practice with the Pinehurst Medical Clinic in Pinehurst, NC for over 10 years. He holds privileges at FirstHealth of the Carolinas, a 4-hospital system in central North Carolina. He serves as the Director of Thoracic Oncology and also the Director of the Chest Center of the Carolinas, a multidisciplinary thoracic oncology clinic. He has previously served as the Medical Director of Critical Care at FirstHealth Moore Regional Hospital (40-ICU beds). He is active in multiple clinical trials as a principal investigator in advanced bronchoscopy, thoracic oncology, molecular pathology, COPD, asthma, and pulmonary arterial hypertension. He has been an author/co-author of multiple studies in these areas.

Dr. Pritchett has most recently published his pioneering work on the use of intraoperative cone-beam CT (CBCT) to assist with the biopsy of peripheral nodules. This technique has been shown to significantly increase the diagnostic yield of guided bronchoscopy for small peripheral nodules. This innovative work with CBCT has led directly to being able to perform first-in-human trials with an FDA-approved device for bronchoscopic microwave ablation of peripheral lung tumors. Dr. Pritchett has also been the first in the U.S. to perform robotic-assisted navigation bronchoscopy with the Intuitive Ion endoluminal robotic platform.


Research / Recognition

Publications

  • NAVIGATE 24-Month Results: Electromagnetic Navigation Bronchoscopy for Pulmonary Leisons at 37 Centers in Europe and the United States. Journal of Thoracic Oncology, December 2021. (Link)
  • Integration of Shape-Sensing Robotic-Assisted Bronchoscopy and Cone-Beam CT for the Biopsy of Pulmonary Nodules. CHEST Meeting Abstract, Vol 160, Issue 4, Supplement A1622-A1624, October 2021 (PDF)
  • Shape-Sensing Robotic-Assisted Bronchoscopy for the Diagnosis of Peripheral Pulmonary Lesions. CHEST Meeting Abstract, Vol 160, Issue 4, Supplement A1631-A1632, October 2021 (PDF)
  • Prospective Multicenter Analysis of Shape-Sensing Robotic-Assisted Bronchoscopy for the Biopsy of Pulmonary Nodules: Results from the PRECISE Study. CHEST Meeting Abstract, Vol 160, Issue 4, A2531-A2533 (PDF)
  • Impact of a Blood-Based Risk Classifier on Management of Benign Pulmonary Nodules in a Real-Word Observational Study. CHEST Meeting Abstract, Vol 160, Issue 4, Supplement A2536-A2538, October 2021 (PDF)
  • Shape-sensing Robotic-Assisted Bronchoscopy for Pulmonary Nodules: Initial Multicenter Experience Using the Ion Endoluminal System. BMC Pulmonary Medicine. October 2021, 21:322. (PDF)
  • Ion: Technology and Techniques for Shape-Sensing Robotic-Assisted Bronchoscopy, August 2021, The Annals of Thoracic Surgery (PDF)
  • Anesthesia Considerations to Reduce Motion and Atelectasis During Advanced Guided Bronchoscopy, July 2021, BMC Pulmonary Medicine Volume 21, 240 (2021) (PDF)
  • NAVIGATE-24 Month Results: Electromagnetic Navigation Bronchoscopy for Pulmonary Lesions at 37 Centers in Europe and the US. March 2021, Journal of Thoracic Oncology, Meeting Abstract (PDF)
  • Lung Navigation Ventilation Protocol to Optimize Biopsy of Peripheral Lung Lesions. March 2021, Journal of Bronchology and Interventional Pulmonology, (PDF)
  • The Impact of Biopsy Tool Choice and Rapid On-site Evaluation on Diagnostic Accuracy for Malignant Lesions in the Multicenter NAVIGATE Study. December 2020, Journal of Bronchology and Interventional Pulmonology, (PDF)
  • Image-Guided Transbronchial Microwave Ablation of Peripheral Primary Lung Tumors with a Flexible Probe: First in US Experience. CHEST (meeting abstract) October 2020, 158(4): A1452-A1453 (PDF)
  • Methods for a Seamless Transition from Tracheostomy to Spontaneous Breathing in COVID-19 Patients. August 2020, Respiratory Care 2020; 10.4187/respcare.08157 (PDF)
  • Prospective Analysis of a Novel Augmented Endobronchial Fluoroscopic Navigation System for Diagnosis of Peripheral Pulmonary Lesions. July 2020, Journal of Bronchology and Interventional Pulmonology, (PDF)
  • A Prospective, Multi-Center Evaluation of the Clinical Utility of the Ion Endoluminal System – Experience Using a Robotic-assisted Bronchoscope System with Shape-Sensing Technology, American Journal of Respiratory and Critical Care Medicine 2020; 201:A2719, Meeting Abstract (PDF)
  • First Look at the Distribution of Risk of Malignancy Pre and Post-Test Using a Blood-Based Biomarker in Patients with Pulmonary Nodules in a Real-World Observational Study, American Journal of Respiratory and Critical Care Medicine 2020; 201: A4465 Meeting Abstract (PDF)
  • Electromagnetic Navigation Bronchoscopy with Tomosynthesis-based Visualization and Positional Correction: Three-dimensional Accuracy as Confirmed by Cone-Beam Computed Tomography. May 2020, Journal of Bronchology and Interventional Pulmonology, (PDF)
  • Society for Advanced Bronchoscopy Consensus Statement and Guidelines for Bronchoscopy and Airway Management Amid COVID-19 Pandemic. April 2020, Journal of Thoracic Disease, 12(5):1781-1789 (PDF)
  • Melting the Tip of the Iceberg: Bronchoscopic-guided Transbronchial Microwave Ablation. April 2020, Translational Lung Cancer Research (PDF)
  • Can an Intratumoral DNA-encoded Immunotherapeutic Device Platform Currently Used in the Management of Cutaneous Lesions be Scaled in Size to Function in the Treatment of Visceral Tumors Through Image-Guided Techniques? Journal of Vascular and Interventional Radiology, March 2020, Meeting abstract, SIR. (PDF)
  • Virtual or Reality: Divergence Between Preprocedural Computed Tomography Scans and Lung Anatomy During Guided Bronchoscopy, March 2020, Journal of Thoracic Disease, 12(4): 1595-1611 (PDF)
  • Novel CBCT-Based Navigation Prototype for Bronchoscopic Biopsy of Peripheral Lung Nodules: A Feasibility Study October 2019, CHEST 156(4): A831-A832 (PDF)
  • Electromagnetic Navigation Bronchoscopy with Advanced Fluoroscopy-Based Localization and Intraprocedural Local Registration for the Evaluation of Peripheral Pulmonary Nodules. October 2019, CHEST 156(4):A2262-A2263;Abstract (PDF)
  • The Impact of Biopsy Tool Choice and Rapid On-Site Evaluation on the Diagnostic Accuracy for Malignant Lesions in the Prospective, Multicenter NAVIGATE Study. October 2019, CHEST 156(4):A827-A829; Abstract (PDF)
  • Pleural Dye Marking of Lung Nodules by Electromagnetic Navigation Bronchoscopy. Clinical Respiratory Journal, September 2019. (Link)
  • Prospective Clinical Validation of the InVisionFirst Lung ctDNA Assay for Molecular Profiling of Patients with Advanced Non-Squamous NSCLC. JCO Precision Oncology, April 2019. (PDF)
  • Fiducial Marker Placement with Electromagnetic Navigation Bronchoscopy; A Subgroup Analysis of the Prospective Multicenter NAVIGATE Study: Therapeutic Advances in Respiratory Disease, Vol. 13: 1-11 - April 2019. (PDF)
  • Tipping Point: Cone Beam CT with Augmented Fluoroscopy for the Biopsy and Treatment of Peripheral Nodules. Journal of Bronchology & Interventional Pulmonology: January 2019, Volume 26, Issue 1, p e13-15 (Link)
  • Electromagnetic Navigation Bronchoscopy for Peripheral Pulmonary Lesions: One-Year Results of the Prospective, Multicenter NAVIGATE Study. Journal of Thoracic Oncology, March 2019: Volume 14, Issue 3, 445-458 (PDF)
  • Cone-Beam CT with Augmented Fluoroscopy Combined with Electromagnetic Navigation Bronchoscopy for Biopsy of Pulmonary Nodules. Journal of Bronchology and Interventional Pulmonology 2018, Volume 25, Number 4 (PDF)
  • A Novel Endobronchial Fluoroscopic Navigation and Localization System: A Summary of a Multicenter LungVision Trial [Abstract]. CHEST. 2018;154(4):880A-882A. (PDF)
  • Safety and Efficacy of Remimazolam Compared with Placebo and Midazolam for Moderate Sedation During Bronchoscopy. CHEST, October 2018, Vol 155, Issue 1, 137-146 (Link)
  • Prospective clinical validation of the InVisionFirst™ ctDNA Assay for Molecular Profiling of Patients with Advanced NSCLC. Meeting Abstract for 19th World Conference on Lung Cancer, IASLC 2018 (Link)
  • Bronchoscopic Image-Guided Microwave Ablation of Peripheral Lung Tumors – Early Results. Meeting Abstract for 19th World Conference on Lung Cancer, IASLC 2018 (Link)
  • Comparison of Pulmonary Nodule Location Between Preprocedural CT and Intraoperative Cone-Beam CT During Guided Bronchoscopy. 2018, Meeting Abstract for 19th World Conference on Lung Cancer, IASLC 2018 (Link)
  • Towards an Optimization of Bronchoscopic Approaches to the Diagnosis and Treatment of the Pulmonary Nodule: A Review. Journal of Thoracic Disease. June 2018, Vol 10, Supplement 14, S1637-S1644 (PDF)
  • Augmented Endobronchial Fluoroscopic Navigation and Localization System: Comparison with Cone Beam CT. American Journal of Respiratory & Critical Care Medicine 2018;197: Meeting Abstract A6156 (PDF)
  • Diagnostic Yield of Electromagnetic Navigation Bronchoscopy for Peripheral Pulmonary Lesions: One-Year Results of the Prospective, Multicenter NAVIGATE Study. Am J Respir Crit Care Med 2018;197: Meeting Abstract A7784 (PDF)
  • Concordance of IHC and a new blood-based expression assay for the detection of PD-L1 in patients diagnosed with NSCLC. Meeting Abstract, AACR/NCI/EORTC 2017 Conference (PDF)
  • Pleural Dye Marking of Lung Nodules by Electromagnetic Navigation Bronchoscopy in the Prospective Multicenter NAVIGATE Study. Meeting Abstract for IASLC 18th World Conference, 2017 (PDF)
  • Electromagnetic Navigation Bronchoscopy to Access Lung Lesions in 1,000 Subjects: First Results of the Prospective, Multicenter NAVIGATE Study. BMC Pulmonary Medicine, April 2016. (PDF)
  • Cone Beam CT-guided Endobronchial Biopsy Assisted by Augmented Fluoroscopy Meeting Abstract for CHEST 2017, Toronto, Canada (PDF)
  • Feasibility of the LungVision Augmented Endobronchial Fluoroscopic Navigation System: Comparison with Cone-Beam CT Scanning for Nodule Localization. Meeting Abstract for CHEST 2017, Toronto, Canada (PDF)
  • Prospective Utility of a Bronchial Genomic Classifier for Lung Cancer Detection: Interim Results from a Multicenter Prospective Registry, Meeting Abstract for CHEST 2017, Toronto, Canada (PDF)
  • Shortening Time from Diagnosis to Treatment in NSCLC: Are Blood-Based Biopsies the Answer: Meeting Abstract, Journal of Thoracic Oncology 2016, Nov;11(11S):S278-S279. (PDF)
  • Cone-Beam CT Scanning with Electromagnetic Navigation Bronchoscopy. Meeting Abstract/Poster presented at CHEST 2014, Austin, TX (PDF)
  • Triple-Needle Brush in the Diagnosis of Peripheral Pulmonary Nodules. Meeting abstract/poster presented at CHEST 2014, Austin, TX (PDF)
  • Aspire Study Group: A Randomized Trial Experience Comparing Emphysematous Lung Sealant Therapy with Medical Therapy for Advanced Emphysema. European Respiratory Journal, 2015 (PDF)
  • Successful Treatment of Refractory Methemoglobinemia with Red Blood Cell Exchange Transfusion Pritchett, M.A., et al. CHEST Meeting Abstracts 2006 130: 294S-a [PDF]

Research

  • Principal Investigator: Targeted Lung Denervation for Patients with Moderate to Severe COPD (AIRFLOW study) 2020
  • Principal Investigator: A Prospective Evaluation of the Clinical Utility for the Ion Endoluminal System (PRECIsE study): A multicenter, prospective trial of a novel robotic bronchoscopy platform. 2019
  • Global Study Principal Investigator: BDX-CD-002 (ORACLE): An Observational Registry Study to Evaluate the Performance of the BDX-XL2 Test
  • Principal Investigator: Multicenter Study of the NeuWave Flexible Ablation Probe in Lung Cancer for Medically Inoperable Patients or Those Who Elect Not to Have Surgery – 2018
  • Principal Investigator: A Patient Registry of the Real-world Use of Orenitram for Pulmonary Arterial Hypertension (ADAPT Study), 2018
  • Principal Investigator: A post-market feasibility study evaluating location accuracy using the superDimension Navigation System V7.2 with Fluoroscopic Navigation Technology in subjects undergoing lung lesion biopsy 2018
  • Principal Investigator: Prospective Observational Multicenter Study to Evaluate the Performance of Inivata Liquid Biopsy Analysis Compared with Standard Tissue Biopsy Analysis for Detection of Genomic Alterations in Patients with Advanced Non-Small Cell Lung Cancer. 2017
  • Principal Investigator: A Multicenter, Randomized, Double-Blinded, Placebo-Controlled Trial to Evaluate the Safety and Efficacy of Inhaled Treprostinil in Subjects with Pulmonary Hypertension due to Parenchymal Lung Disease. INCREASE Study. 2017
  • Principal Investigator: A Multicenter, Randomized, Double-Blinded, Placebo-Controlled Study to Evaluate the Safety and Efficacy of Oral Treprostinil in Subjects with Pulmonary Hypertension (PH) in Heart Failure with Preserved Ejection Fraction (HFpEF). SOUTHPAW Study. 2017
  • Principal Investigator: BioSpecimen Collection for Use in the Development and Validation of PD-L1 Biomarker Tests and Technologies. Biodesix, Inc. 2017.
  • Principal Investigator: Bronchoscopic Lung Biopsy Enhancement with LungVision Device. 2017
  • Principal Investigator: PAION: Efficacy and Safety of Remimazolam in ASA III/IV Patients Undergoing Endoscopy. 2016
  • Principal Investigator: NAVIGATE Trial: Clinical Evaluation of superDimension System for Electromagnetic Navigation Bronchoscopy. 2016
  • Principal Investigator: ASCENT Trial: Double-blind, Randomized, Placebo-controlled, Parallel-group, Phase IV Study to Evaluate the Effect of Aclidinium Bromide on Long-term Cardiovascular Safety and COPD Exacerbations in Patients with Moderate to Severe COPD. 2015
  • Principal Investigator: Phase III study to demonstrate the safety and efficacy of AeriSeal System treatment plus optimal medical therapy compared in patients with advanced upper lobe predominant (ULP) heterogeneous emphysema. 2015
  • Principal Investigator: Post-marketing observational study to assess respiratory tract adverse events in pulmonary arterial hypertension patients being treated with inhaled prostacyclin therapy (Tyvaso). 2014